Government-backed Start Up Loans can help you break through barriers to work. These can range from £500 to £25,000 at a fixed interest of 6% per year. You can repay this between 1 and 5 years. Read more about Start Up Loans.
If you need flexible working hours or to work from home, have a conversation with any new client. Being open with clients from the start can help you get work that suits your needs. Not everyone will agree to your conditions. But being self-employed allows you to choose the jobs you want and reject those that create barriers for you.